FimH and Anti-Adhesive Therapeutics: A Disarming Strategy Against Uropathogens
نویسندگان
چکیده
منابع مشابه
Development of a Novel Anti-Adhesive Vaccine Against Pseudomonas aeruginosa Targeting the C-terminal Disulfide Loop of the Pilin Protein
The type IV pili (T4P) is a major virulence factor of Pseudomonas aeruginosa (P. aeruginosa) that is associated with primary adhesion, biofilm formation and twitching motility. This study focuses on the introduction of a novel biologically active subunit vaccine derived from the disulfide loop (DSL) of P. aeruginosa pilin. We investigated the expression of the novel PilA in-frame with pET26a ve...
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ژورنال
عنوان ژورنال: Antibiotics
سال: 2020
ISSN: 2079-6382
DOI: 10.3390/antibiotics9070397